Publications


Inhibitors of the NAD+-Dependent Protein Desuccinylase and Demalonylase Sirt5.
B. Maurer, T. Rumpf, M. Scharfe, D. A. Stolfa, M. L. Schmitt, W. He, E. Verdin, W. Sippl, M. Jung; ACS Med. Chem. Lett. (2012) in press.

 

The discovery of novel and highly selective 10,11-dihydro-5H-dibenz[b,f]azepine SIRT2 inhibitors.
P. Di Fruscia, K.-K. Ho, S. Laohasinnarong, M. Khongkow, S. H. B. Kroll, S. A. Islam, M. J. E. Sternberg, K. Schmidtkunz, M. Jung, E. W.-F. Lam, M. J. Fuchter; Med. Chem. Commun. 3 (2012) 373-378.

 

Zerlotini, A; Aguiar, E; Yu, F; Xu, H; Li, Y; Young, N; Gasser, R; Protasio, A; Berriman, M; Roos, D; Kissinger, J; Oliveira, G. SchistoDB: an updated genome resource for the three key schistosomes of humans. Nucleic Acids Research, Nucleic Acids Research, 2012, 1–4. 

 

Pierce RJ, Dubois-Abdesselem F, Lancelot J, Andrade L, Oliveira G. Targeting Schistosome histone modifying enzymes for drug development. Curr Pharm Des. 2012. 18(24):3567-3578.

 

Nahum, L., Mourão, M.M., Oliveira, G. New frontiers in Schistosoma genomics and transcriptomics. Journal of Parasitology Research, 2012, Article ID 849132.

 

Anderson, A., Pierce R.J., Verjovski-Almeida, S. (2012) Schistosoma mansoni histones: from transcription to chromatin regulation; an in silico analysis. Mol. Biochem. Parasitol. 183, 105-114.

 

Pierce, R.J., Dubois-Abdesselem, F., Caby, S., Trolet, J., Lancelot, J., Oger, F., Bertheaume, N., Roger, E. (2011) Chromatin regulation in schistosomes and histone-modifying enzymes as drug targets. Mem. Inst. Oswaldo Cruz, Rio de Janeiro, 106, 794-801.